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Mouton-Liger, F
While vascular TJ alterations and serum protein extravasation are predominantly observed within MS lesions, they are also present in seemingly normal white and gray matter, suggesting a more extensive and systemic impairment of BBB integrity [130,131,132,133]
The clinician can also help determine whether standard care, physical therapy, imaging, nutrition, sleep optimization, hormone evaluation, or another treatment should come first
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