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Description

Inhibiting the IRE1 axis of the unfolded protein response enhances the antitumor effect of AZD1775 in TP53 mutant ovarian cancer

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It can occur by three main mechanisms, which lead to absence of expression of paternally inherited genes in the 15q11.2q13 region: paternal microdeletion, maternal uniparental disomy, and imprinting defect

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Anh FF, Roy D, Pilon G, Dudonn S, Matamoros S, Varin TV, et al

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