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Drugs that raise blood glucose (such as corticosteroids, certain antipsychotics, or thiazide diuretics) may counteract glycaemic benefits
Diabetes Care, 1997, Vol 20(3), pp 244247
Overall, anti-metabolic drugs performed the best in both aspects, with odds ratios of 2.15 and 1.35, while anti-fibrotic drugs showed ratios of 0.86 and 1.11
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Thus, changes in the GSH/GSSG ratio are fundamental in the fine-tuning of signal transduction, even under mild oxidative stress that underlies physiological events such as cell cycle regulation and other cellular processes (Schafer and Buettner, 2001)
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