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Several injectable dual GLP-1 receptor and glucagon receptor (GCG) agonists are in phase-2/3 clinical trials (Survodutide, Boehringer-Ingelheim/Zealand Pharma
Caution and close monitoring are warranted in individuals with preexisting diabetic retinopathy, due to a higher incidence of retinopathy-related complications observed in clinical trials, particularly with semaglutide (52)
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