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SULT1A1 also takes part in transformation of hydroxymethyl polycyclic aromatic hydrocarbons, hydroxyderivatives of arylamines, allylic alcohols and heterocyclic amines to their reactive intermediates which are able to bind to nucleophilic structures such as DNA and consequently act as mutagens and carcinogens (Glatt et al., 2001)
NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression
Lam C, Tan W, Leighton M, et al
PMID: 16763210
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