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They are designed to work on the same receptors as the natural hormone but more strongly or for longer, which is why they are typically taken weekly rather than daily
What about oral supplements
To sum up, the potential mechanisms of delayed gastric emptying by GLP-1 are mainly related to: (1) decreasing the contractile force of the gastric antrum and duodenum and increasing the pyloric tension (Schirra et al., 2000
Semba RD, Trehan I, Li X, et al
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