Seek urgent medical attention if you experience: Severe, persistent abdominal pain (especially if radiating to the back) with or without vomiting, which could indicate pancreatitis Right upper quadrant pain, fever, or yellowing of the skin/eyes, which might suggest gallbladder disease Severe chest pain, difficulty breathing, facial swelling, or signs of an allergic reaction For urgent advice, call NHS 111
In our clinical experience, patients who follow the escalation schedule faithfully tend to tolerate the medication well and achieve better long-term adherence
Endocr Rev (2003) 24(5):63367
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