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Center for Digestive and Liver Diseases, Nara City Hospital, Nara, Japan Sapienza University of Rome, Unit of Rheumatology, Rome, Italy Enrico Arosio, MD, Sergio De Marchi, MD and others
Patients should contact their healthcare provider if gastrointestinal side effects do not improve after 68 weeks at a stable dose, as this may indicate poor tolerance requiring dose adjustment or medication discontinuation
doi:10.1016/j.amjmed.2023.07.016 176
However, the timeline for appetite suppression can vary based on dosage, adherence, metabolic differences, and lifestyle factors
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