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T-DXd has a high drug-to-antibody ratio and membrane-permeable payload, allowing a bystander effect even in tumors with heterogenous or low HER2 expression 169
On paper, the combination addresses both sides of the energy balance equation through complementary mechanisms
UV exposure on freshly treated skin is the leading driver of post-inflammatory hyperpigmentation across all skin types but the consequence is more visible and more durable in darker tones
Eine hufig zitierte Dosis in Rattenmodellen liegt bei etwa 10 g/kg, in manchen Studien wurden auch 10 ng/kg getestet
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