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This chronic bile acid exposure can trigger diarrhea, nutrient malabsorption, and increased intestinal fluid secretiona condition sometimes called post-cholecystectomy syndrome

So if Phase 3 data lands in late 2025, FDA approval might come in 2026, TGA submission in late 2026, TGA approval in 2027 or 2028, and PBS listing potentially 2029 or later

Advanced glycation end products in the skin: molecular mechanisms, methods of measurement, and inhibitory pathways