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Interestingly, activated CD8+ cytotoxic T cells were upregulated in GAN DIO-NASH-HCC mice, which has been linked to HCC and impaired responses to immune therapies in NASH-HCC 12

doi: 10.3389/fendo.2023.1205219 Received 13 April 2023 Accepted 10 July 2023 Published 26 July 2023 Volume 14 - 2023 Edited by Pingping Han, The University of Queensland, Australia Reviewed by Bruno Guigas, Leiden University, Netherlands

doi: 10.3390/ijms20174092 29 GallwitzB

Your treatment duration will depend on factors like your starting weight, your goals, how well you tolerate the medication, your overall health, insurance coverage, and whether youre also developing sustainable habits alongside the medication