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Studies have found that Megasphaera is a dominant genus of gut microbiota in different life stages of primates, and is also a key driving factor for the long-term development of gut microbiota in adults [72]
Medical Strategies to Manage the Odor Because the odor is caused by unabsorbed L-carnitine reaching the gut bacteria, medical management strategies focus on improving absorption, reducing the supplement load, or altering the gut bacteria [6] [7]
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This work aimed to evaluate protocol adherence to the SPIRIT PRO guidelines and identify protocol-level gaps in PRO implementation in interventional paediatric oncology trials
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