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The dose-finding phase 2 trial randomised 706 adults with obesity, or overweight plus at least one weight-related comorbidity, to once-weekly cagrilintide at 0.3, 0.6, 1.2, 2.4 or 4.5 mg, weekly placebo, or daily liraglutide 3.0 mg as an active comparator, all alongside lifestyle intervention
Navigating this tension requires planning, clear communication with providers, realistic expectations about weight management during pregnancy planning, and commitment to maintaining lifestyle changes when medication is discontinued
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Comprehensive programs often include: Initial consultation Medical evaluation Nutrition support Activity recommendations Progress monitoring Dose adjustments Follow-up appointments The goal is to support sustainable, long-term health improvements rather than rapid short-term weight loss
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