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Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency
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Due to its plasma half-life of approximately 3.8-6.9 hours, a twice-daily (BID) dosing schedule may be used to provide more consistent and sustained inhibition of NNMT throughout the day, potentially maximizing its metabolic effects
Suppression of colorectal cancer subcutaneous xenograft and experimental lung metastasis using nanoparticle-mediated drug delivery to tumor neovasculature
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