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In a prospective cohort study involving a clinical population of 1,228 women of childbearing age who were planning to conceive naturally, those who were exposed to SSRIs experienced a 24% reduction in the ability to conceive, with fluoxetine exerting an even more pronounced effect than other SSRIs, as well as a 9% reduction in the incidence of live births

No specific high-affinity receptor has been identified in the published peer-reviewed literature, and current mechanism proposals are drawn from observed effects in preclinical models rather than direct receptor pharmacology

Its a formidable, high-tech biologic medication that represents a significant leap forward in cardiovascular medicine

DSIP appears to interact with NMDA receptors, components of the MAPK signaling cascade, and glucocorticoid pathways