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These central effects translate into substantial weight loss - typically 5%-15% of body weight with current GLP-1 RAs - which directly ameliorates hepatic steatosis by reducing adipose tissue mass, reducing hepatic free fatty acid influx, and improving insulin sensitivity
If persistent irritation, dermatitis, or pigmentary changes occur, stop and consult a dermatologist
Endocr Rev (1999) 20:876913
Eat a well-balanced diet with a mix of fruits and vegetables, whole grains, and lean protein
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