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The relationship between common pathogenic variants and the phenotypic syndromes of mitochondrial diseases is summarized in Table 2
Key Takeaway: Long-term glutathione use is widely considered safe
This effect may be attributed to a marked reduction in the expression of MuRF1 and atrogin-1, thereby delaying age-dependent dysregulation of muscle mass through the modulation of genes involved in muscle regeneration and catabolism (66)
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