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Acute Gallbladder Disease In clinical trials of ZEPBOUND, cholelithiasis was reported in 1.1% of ZEPBOUND-treated patients and 1% of placebo-treated patients, cholecystitis was reported in 0.7% of ZEPBOUND-treated patients and 0.2% of placebo-treated patients, and cholecystectomy was reported in 0.2% of ZEPBOUND-treated patients and no placebo-treated patients

In a letter to the FDA, the Attorneys General said online retailers are illegally selling the active ingredients of GLP-1 drugs directly to consumers, without a prescription. According to the letter, those retailers claim that the active ingredients they sell are for research purposes only or not for human consumption. Fitch said the active ingredients come from unregulated, undisclosed sources, which could pose the risk of contamination

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