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May extend shelf life to: 45-60 days depending on formulation Pharmacy should provide specific expiration guidance If unsure: Follow standard 28-30 day rule
What are the theoretical and long-term risks
USA 115 , 1017810183 (2018)
While, extravascular RBC destruction by the reticuloendothelial system predominately occurs in the spleen and liver, RBCs have been shown to infiltrate the vascular endothelium in early atherosclerotic plaques 64
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