The first week on semaglutide: realistic expectations Your first week on semaglutide is primarily about adjustment, not results
In the Lira Pump study, they decreased basal insulin by 10%, but increased bolus by 15% ( Our current practice is to consider a ~20% bolus insulin decrease and a ~10% basal insulin decrease before GLP-1RA initiation, although prior A1c, risk of hypoglycemia, potential risk of ketosis due to reduced insulin doses, as well as other patient-specific factors should guide the final insulin dose changes
Nowadays, the most common cause of systemic complications and cirrhosis of the liver is known to be induced by MASLD, which usually starts with lipid droplet accumulation within hepatocytes, causing lipotoxicity and inflammation, magnified according to the genetic susceptibility of affected individuals
A co-worker received a text which is, unfortunately, becoming more common