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It is currently completing Phase 3 TRIUMPH trials and is available for research use in lyophilized (freeze-dried powder) form for the latest on [when retatrutide will be FDA approved](/guides/retatrutide-fda-approval-2026-timeline-status), see our regulatory timeline tracker
Type 2 diabetics typically have higher levels of blood glucose resulting in higher-than-normal readings
Randomized trials (direct AD studies) Liraglutide (ELAD Phase 2b): In people with mild AD, 12 months of liraglutide slowed brain atrophy (MRI) and was associated with an ~18% slower cognitive decline versus placeboencouraging but still preliminary and not yet a practice-changing Phase 3 outcome
1 Originally FDA-approved for type 2 diabetes, GLP-1 RAs also lead to sustained weight loss and have revolutionized diabetes and obesity management
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