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Furthermore, GSTs are additionally identified as regulators of cellular signaling pathways, thereby influencing cell proliferation or apoptosis ( in vitro with chemically reactive metabolites derived from several drugs displaying idiosyncratic toxicity, including troglitazone, acetaminophen, clozapine, and diclofenac ( HepG2 cells have been used for decades as a test system for studies involving hepatotoxic compounds

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The clinical benefit of liraglutide 3.0 mg was mostly mediated by its effect on BW, as treatment assignment was not associated with change in AHI independently of weight reduction 20

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Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain

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Do KQ, Cabungcal JH, Frank A, Steullet P, Cuenod M

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