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prolonged exposure to estrogen

doi: 10.1016/j.biopha.2018.09.049 94 XinWZhaoXLiuLXuYLiZChenLet al

The ratio may be low because SAM is low, SAH is elevated or both

Supplementing with specific nutrients, like iron, omega-3s, B12, L-carnitine, and magnesium, can help reduce fatigue by restoring nutrients to proper levels