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SARMs, such as enobosarm and RAD140, selectively bind to androgen receptors in skeletal muscle and bone, resulting in increased lean body mass, improved muscle strength, and enhanced physical performance [120]

[1] [2] Administered as a weekly subcutaneous injection, this medication works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways

Medication-related weight change can also have more than one cause

The dose is usually started low and then slowly increased over several weeks to help the body adjust and lower the chance of side effects