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Lancet Haematol

Several bacterial fermentation pathways have been proposed to lower cholesterol levels, including bile acid-converting and SCFA-producing enzymes which may reduce the rate of cholesterol reabsorption and increase cholesterol metabolism 76

Its also important to remember that GLP-1 treatment is a long-term commitment, as most people stay on these medications for an extended period

At a genome-wide significant level, three loci (ABCG2, SLC2A9, and CUX2) have been identified in association with renal urate overload, whereas four loci (ABCG2, SLC2A9, CUX2, and GCKR) have been linked to renal urate underexcretion