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74 In one randomized, placebo-controlled, crossover trial that included 24 healthy participants aged 55 years and older who had no major sleep issues, 5 mg melatonin 30 minutes before bedtime in controlled experimental conditions increased sleep efficiency, mainly by increasing stage 2 NREM sleep and slightly shortening awakenings

Less is more with this ingredienta pea-sized amount typically covers the entire face

And they point the way to a new class of antidepressants that could be freer of side effects and faster-acting than those in use today, and that may help patients for whom existing treatments don't work or have stopped working