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These outcomes vary according to concentration, exposure duration, and experimental model, making GHKCu a versatile tool for studying copperdependent signalling and peptidemetal interactions in both in vitro and in vivo contexts
Daily use at 0.1% beats occasional use at higher concentrations
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However, they have limited or no efficacy against certain emerging Candida species, such as Candida auris and Candida parapsilosis , highlighting a growing concern regarding their spectrum of activity (Roemer and Krysan, 2014)
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