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They work by imitating glucagon-like peptide-1 (GLP-1), a growth hormone that triggers insulin release, reduces blood sugar levels, slows the passage of food along the intestinal tract and stimulates parts of the brain that control craving and satiety
It has also been shown to lower homocysteine levels, a molecule linked to inflammation and cognitive decline, with longitudinal studies linking optimal B12 levels with improved cognitive function, mood and reduced risk of neurodegenerative disease
Vomiting can happen with retatrutide, especially at higher doses or after dose increases
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