Em estudos pr-clnicos (estudos em animais), os anlogos de GLP-1 aumentaram o risco de cncer medular de tireoide (CMT)
Meanwhile, GLP-1 receptor agonists, such as semaglutide and liraglutide, enhance insulin secretion, suppress appetite, and slow gastric emptying, facilitating weight loss
This guide examines the science behind each peptide with relevance to lupus, explores practical considerations for researchers, and provides evidence-based context for understanding how these molecules interact with autoimmune pathology
doi: 10.1021/jacsau.2c00130 de Bray A, Roberts AG, Armour S, Tong J, Huhn C, Gatin-Fraudet B, Romann K, Shilleh AH, Jiang W, Figueredo Burgos NS, Trott JPP, Viloria K, Nasteska D, Pearce A, Miyazaki S, Tomlinson JW, Owen DM, Nieves DJ, Ast J, Cyranka M, Epanchintsev A, mml C, Reimann F, Soykan T, Ladds G, Adriaenssens AE, Trapp S, Jones B, Broichhagen J, Hodson DJ