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Skin elasticity using a cutometer was measured at baseline, at 4 weeks, and then 4 weeks after discontinuation of the treatment, which showed significant improvement in skin elasticity, even in sun-exposed skin areas, during these time points compared with baseline values [39]
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Recent studies have shown that glutamine-derived -KG regulates the differentiation of CD4(+) T cells into Th1-type effector T cells or Treg cells via DNA methylation and lipid homeostasis 135,136
To understand those dysfunctions, discussed below is both how oligodendrocytes behave in natural myelination and how glial cells interact in its disruption
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