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[3] NNMT sits at an intersection of two important resource pools: it consumes SAM (the cells universal methyl donor) and it draws on nicotinamide that would otherwise feed the NAD salvage pathway

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In 2015, 32 white rabbits were divided into four groups of eight, and each group was given a placebo, AOD 9604, hyaluronic acid, or a combination of AOD 9604 and hyaluronic acid for 4 to 7 weeks