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Mental Health Concerns Like Suicidal Thoughts Mental health concerns became an issue of importance with GLP-1 agonists when the Food and Drug Administrations Adverse Event Reporting System received numerous reports of individuals who reported suicidal thoughts and ideations while taking GLP-1 agonist drugs

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What makes the triple agonist approach so compelling is how it leverages glucagon to increase energy expenditure alongside the appetite suppressing effects of GLP-1 and GIP