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Activation of these sensors initiates checkpoint cascades, most notably ATMChk2 and ATRChk1, which coordinate cell cycle arrest, DNA repair pathway selection and apoptosis or senescence when repair fails

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Potential side effects include: Gastrointestinal trouble, such as nausea, vomiting, constipation, diarrhea, and abdominal pain Hyperglycemia (low blood sugar), which can lead to blurred vision, sweating, anxiety, dizziness, shakiness, headaches, slurring speech, hunger, or weakness Elevated heart rate Kidney failure Medullary thyroid cancer (also known as medullary thyroid carcinoma) Severe allergic reaction If you experience any severe side effects, inform your healthcare provider immediately

These bodily responses work together to reduce a patients appetite and slow gastric emptying