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Both medication types also commonly influence appetite and weight, as they act on overlapping hormonal and reward pathways in the brain (Srinivasan et al., 2025)

Using the same spot repeatedly can lead to lipohypertrophy, which are fatty lumps under the skin that interfere with how well your body absorbs the medication

Caroline Apovian, a professor of medicine at Harvard Medical School and co-director of a weight-loss center at Brigham & Women's Hospital in Boston, told WSJ that Ozempic may trigger strange dreams because it promotes the production of a gut hormone that has receptors in the brain

The Journal of clinical endocrinology and metabolism, 104(10), 46604666