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For instance, while adequate glutathione levels are essential for heart health, an overloadparticularly in the context of oxidative stressmay lead to dysfunction in heart cells
However, indirect interactions warrant consideration: Gastrointestinal Effects: Wegovy commonly causes nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
& Gilja, O
Mechanistically, LONP1 promotes proliferation and migration of pulmonary artery smooth muscle cells by directly binding to and degrading mitochondrial pyruvate carrier 1 (MPC1), leading to pulmonary vascular remodeling and ultimately promoting the development of PH [76]
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