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Although it may sound like a single condition, Ehlers-Danlos Syndromes (EDS) are a heterogeneous group of hereditary disorders of connective tissue, with common features including joint hypermobility, soft and hyperextensible skin, abnormal wound healing, and easy bruising

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Retatrutide-specific body-weight data has not been published, but semaglutide and tirzepatide studies measured 20% to 40% higher exposure in people weighing 120 to 155 lb than in a 185 lb reference

Together, these peptides work across complementary pathways involved in repair, inflammation, circulation, and skin and gut health