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We found that many metabolites were significantly reduced in one and/or two 13 C-labelling (see Fig
In conclusion, vitamin B6 plays a crucial role in the nervous system, serving as a cofactor in reactions related to amino acid metabolism and the synthesis of neurotransmitters such as dopamine, serotonin, and GABA, as well as playing a significant part in the methylation of homocysteine (6, 11, 1618, 57, 58)
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There are some oxidoreductases, whose activity depends on proximal histidine-asparagine interactions (e.g
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