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Aging, chronic stress, environmental exposure, poor sleep, and illness can all deplete levels over time, says Patel
Across these trends, theres a strong emphasis on polished yet low-maintenance looks that balance sophistication with ease of application
For example, the cystine/glutamate antiporter SLC7A11, the main route of cysteine acquisition, and the glutamate cysteine ligase modifier subunit (GCLM), which is necessary for the efficient synthesis of GSH, are upregulated in the tumor cells during oxidant stress to increase the GSH synthesis
Unfortunately, theres much in todays world that promotes excess free radicals, such as: Pollution High blood sugar levels Alcohol Smoking Infections Exposure to sunlight (radiation) If you combine these outside promoters of free radicals with the fact that many people fall short on antioxidants, you can see why oxidative stress is so common
