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The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)
Patients should maintain realistic expectations and continue treatment as prescribed, even if immediate improvements are not apparent, as premature discontinuation can lead to symptom recurrence
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