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Girgis added that common side effects of Ozempic and Wegovy may trigger mental health side effects
PubMed 10.Liu A, Bech P, Fridhammar A, Nilsson A, Willis M, Nuhoho S
In SURPASS 4 The risk of suffering from any major adverse cardiovascular event MACE-4 and MACE-3 (including myocardial infarction, stroke, hospitalization for angina, and all-cause death) with the highest dose of tirzepatide (15 mg per week) has been estimated at 050 (026095), which was intended to provide initial proof of the cardiovascular safety of tirzepatide [2, 5]
In preclinical studies, GLP-1 receptor agonists reduce self-administration of opioids, attenuate drug-seeking after periods of abstinence, and blunt stress-induced relapse
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