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Chronic Inflammation Linked to Metabolic and Heart Disease Chronic inflammation creates a domino effect: It stiffens arteries, triggering high blood pressure and a greater risk of heart attacks and strokes. Cells become more resistant to insulin, making diabetes more likely and harder to control

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A contribution of NTS astrocytes to the appetite suppression caused by acute GLP-1R agonists also seems possible from evidence showing (1) expression of GLP-1Rs in this cell type, (2) functional responses of astrocytes to exendin-4 and liraglutide, and (3) negation of appetite suppression from administration of exendin-4 into the NTS when astrocyte metabolism is selectively inhibited in this region [56]

Because of its essential role in cellular wellness, glutathione is often described as one of the bodys most important internal antioxidants