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GSH + amino acid -Glu-amino acid +CysH-Gly (amino group transfer) GSH + H2O Glu +CysH-Gly (hydrolysis) GSH + GSH -Glu-GSH +CysH-Gly (amino group transfer) 3

Once ingested or injected, niacinamide is converted to nicotinamide mononucleotide (NMN) and then to NAD+ through the salvage pathway

Our work highlights B cell-specific alterations that offer novel insights for the understanding of the role of GSH in the regulation of B cells function and defects during disease, such as those caused by viral infections