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Whilst it is employed by many rate limiting biochemical steps in the body our understanding of its role in the immune system management of cytokine driven inflammation is only just evolving.[4] This represents an area of increasing research as the role of the mucosal immune system becomes attributed to persistent Para Inflammation and the degenerative conditions assosciated with it
Its likely that GLP-1 RAs (or their combinations) will be part of a future MASH therapy regimen, given weight loss is the cornerstone treatment and GLP-1 causes weight loss plus some direct hepatic fat reduction
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