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IGF-1R Receptor Binding and Downstream Signalling Both IGF-1 and des-(1-3)IGF-1 bind only to the type 1 IGF receptor in L6 myoblasts, rat vascular smooth-muscle cells, and human lung fibroblasts, with binding potencies in the order des-(1-3)IGF-1 greater than IGF-1 a difference attributed to the lower affinity of des-(1-3)IGF-1 for the competing IGFBP rather than superior intrinsic receptor affinity
At 16.67 mg/mL, those doses equal 6, 9, and 12 U-100 units [18]
The International Journal of Biochemistry & Cell Biology, 37 (8), 1727-37
Recently, it was shown that cytosolic lipid droplets, which are known to protect cancer cells from starvation-induced death, increased in content with increased cell density in HeLa cells 38
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