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Practical Diabetes 37(5):194195
The authors concluded that lubiprostone produced a bowel movement in the majority of individuals within 24 h of initial dosing, with sustained improvement in frequency and other constipation symptoms over 4 weeks
Pharmaceutical-grade material goes through stricter purity tests (98% by HPLC), a full impurity profile, endotoxin testing below 0.01 EU/g, and heavy metal screening that meets ICH Q3D standards
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