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This pricing dynamic constrains overall market penetration and slows adoption despite the strong clinical benefits of GLP-1 therapies in weight management and glycemic control, making cost a key obstacle to broader global uptake
As GLP-1 RAs exert multiple metabolic effects, including the regulation of glucose homeostasis, it is logical to assume that they may also affect the secretion of GH
Once those are in place, peptides can help tip the scales in a more favorable direction
Mol Cell Endocrinol 220(1-2):17 Casarini L, Santi D, Brigante G, Simoni M (2018) Two hormones for one receptor: evolution, biochemistry, actions, and pathophysiology of LH and hCG
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