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Visible changes in tone and firmness appear at 4 to 8 weeks

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"FDA Response to three Citizen Petitions against biosimilars" (PDF), FDA , 30 May 2006, archived from the original (PDF) on June 19, 2006, retrieved 23 November 2015 In 2023, the FDA approved a different sustained-release form of growth hormone, Sogroya (somapacitan-beco) (Novo) for both pediatric patients (2.5 years and older) and adult patients, whom have growth failure due to inadequate secretion of endogenous growth hormone (rHGH)