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We compared the activity of wild-type BoNT/X and X(PC) on fusion proteins containing the targeted regions of either procaspase-1 (residues 304320) or VAMP1 (residues 2888), inserted between maltose-binding protein (MBP) and glutathione S -transferase (GST) proteins to facilitate bacterial expression and purification of these substrates
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It offers a promising avenue for reducing cardiovascular risk in a significant portion of the population grappling with metabolic syndromes
Davies MJ, Bajaj HS, Broholm C, et al
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