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A drug that was truly protecting neurons would be expected to lower a marker of axonal injury, not raise it, so the pattern of falling pathology markers alongside rising damage markers is difficult to read as neuroprotection
As early as March 2021, the WHO Regional Office for Europe developed protocols and guidelines for long COVID with several countries following suit on developing their own strategies
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In an ideal case, a design that does not bind gives a flat line, whereas for a binder, a clear rise and fall is present, and a set of equations can be fit to the curves to compute an affinity
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