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(eClinicalMedicine) found that 52 weeks of once-weekly semaglutide reduced hip bone mineral density by 2.6% and lumbar spine density by 2.1% compared to placebo, with increased bone resorption and no compensatory increase in bone formation
They also received oral administration of saline (2 ml/kg body weight) once daily for 56 consecutive days
Any such use is purely experimental and speculative
The firm also said Vikings plan to develop both injectable and pill-based versions of its treatment could help the company serve a wider range of patients and make long-term treatment easier to maintain
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